Nutraceutical

• “Andrographis paniculata (Burm. f.) Nees (Acanthaceae) is a medicinal plant used in many countries.”
• “Its major constituents are diterpenoids, flavonoids and polyphenols.”¹

Researchers from Department of Biochemical Science and Technology, College of Life Science,
National Taiwan University, Taipei, Taiwan, China; have presented an article titled: “Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian).”

The researchers from Department of Biochemical Science and Technology, College of Life Science,
National Taiwan University, Taipei, Taiwan, China; have also noted:

• “Among the single compounds extracted from A. paniculata, andrographolide is the major one in terms of bioactive properties and abundance.”
• “Among the andrographolide analogues, 14-deoxy-11,12-didehydroandrographolide is immunostimulatory, anti-infective and anti-atherosclerotic; neoandrographolide is anti-inflammatory, anti-infective and anti-hepatotoxic; 14-deoxyandrographolide is immunomodulatory and anti-atherosclerotic.”
• “Among the less abundant compounds from A. paniculata, andrograpanin is both anti-inflammatory and anti-infective; 14-deoxy-14,15-dehydroandrographolide is anti-inflammatory; isoandrographolide, 3,19-isopropylideneandrographolide and 14-acetylandrographolide are tumor suppressive; arabinogalactan proteins are anti-hepatotoxic.”
• “The four flavonoids from A. paniculata, namely 7-O-methylwogonin, apigenin, onysilin and 3,4-dicaffeoylquinic acid are anti-atherosclerotic.”

(1) Chao WW, Lin BF: Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian). Chin Med. 2010 May 13;5(1):17; (Article in Press)